An official or real " Uncharted 2 " ISO file for the PSP does not exist because the game was never released for the PlayStation Portable (PSP).
Fan-Made Mods: Many creators have taken existing PSP games (like Tomb Raider: Anniversary or Indiana Jones) and swapped the character models for Nathan Drake. These "total conversion mods" are often labeled as Uncharted games to attract downloads. Uncharted 2 Psp Iso Download
This is the closest you will get to an “Uncharted 2 PSP” experience. Eye of Indra is a motion-comic prequel that explains how Nate met Rika Raja and Eddy Raja. It features voice acting, sound effects, and animated panels. You can still find the original files to transfer to a hacked PSP, but it is not a 3D action game. An official or real " Uncharted 2 "
Timeline: It is a prequel to the first game, Drake's Fortune. It features voice acting, sound effects, and animated panels
Users are strongly advised to avoid downloading these files to protect their devices and personal data, and instead utilize legitimate platforms like the PS Vita or Remote Play to experience the franchise on the go.